Optical coherence viscometry.

Hsiao-Chuan Liu,Matthew W Urban

doi:10.1063/5.0048608

Abstract

We report a technique, named optical coherence viscometry (OCV), to measure the viscosity of Newtonian fluids in a noncontact manner. According to linear wave theory with small amplitudes, capillary waves are associated with fluid mechanical properties. To perform this measurement and avoid the overdamped effects of capillary waves in viscous fluids, transient acoustic radiation force was applied to generate capillary waves. Within a very limited field-of-view using optical coherence tomography, wave motion acquired in the time domain was analyzed using Fourier methods to study the wave velocity dispersion and attenuation relationships for capillary waves, which can reduce the fluid quantity drastically into tissue culture scale. We measure the viscosities of water, water–glycerol solutions with three concentrations, and biological plasma using the proposed OCV and compare the experimental results to theoretical calculations. OCV is sensitive to wave perturbations and can be a promising technique for measuring the viscosity of biological fluids and could be applied in future applications for measurements for lipid membranes in cell biology and tissue engineering investigation.

Highlights

By applying an electric field, capillary waves can be produced with a noncontact approach.11 a controlled environment is required to avoid mechanical disturbances and air currents which could damage cellular or molecular components in biological media
We report a technique, named optical coherence viscometry (OCV), to measure the viscosity of Newtonian fluids in a noncontact manner
Within a very limited field-of-view using optical coherence tomography, wave motion acquired in the time domain was analyzed using Fourier methods to study the wave velocity dispersion and attenuation relationships for capillary waves, which can reduce the fluid quantity drastically into tissue culture scale

Summary

Introduction

By applying an electric field, capillary waves can be produced with a noncontact approach.11 a controlled environment is required to avoid mechanical disturbances and air currents which could damage cellular or molecular components in biological media. To perform this measurement and avoid the overdamped effects of capillary waves in viscous fluids, transient acoustic radiation force was applied to generate capillary waves.

Results

Conclusion