Abstract
To describe the optical coherence tomography (OCT) features of multifocal vitelliform macular dystrophy (VMD). Five patients (10 eyes) with multifocal VMD were examined by slit lamp biomicroscopy, fundus photography, and OCT. Serous retinal detachment was present in the macular area in all eyes. A hyperreflective inner/outer segment interface was observed in the macula in nine of them. High reflectivity was homogeneous in six eyes of three patients with no prominent macular lesion. Retinoschisis-like changes could be clearly seen in four eyes evaluated by high-resolution OCT. A hyporeflectivity corresponded to the inner nuclear layer in two eyes. In four eyes with prominent macular lesions, a hyperreflective area between the hyporeflective outer nuclear layer and the hyperreflective retinal pigment epithelium layer was detectable. Although the fundus appearance of multifocal VMD is quite variable, OCT features of the disease are relatively uniform. Optical coherence tomography could help the pathological interpretation and facilitate the diagnosis of VMD.
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