Abstract
The possibilities of nutrigenomics as an approach to determining the effectiveness of specialized food products have been studied. For this purpose, the influence of consumption of whey protein concentrate FitPROTEIN and the carrier of branched-chain amino acids SPORTAMIN®BCAA 6000 on the expression of the target gene FTO was determined. Despite a certain similarity in the composition of these products, their effect on the average level of FTO gene expression is significantly different. The results obtained are discussed from the standpoint of identification of the target gene, detection of gene polymorphism, analysis of expression data and the possibility of updating these procedures using digital technologies. An algorithm for evaluating the effectiveness of specialized food products based on nutrigenomic studies is proposed. Nevertheless, it seems promising to transfer experimentation to the virtual sphere through the use of digital twins, including in combination with the Internet of Things.
Highlights
As is known, the world market for health-improving, functional and sports food products is growing steadily, especially in Western countries
Two specialized food products (SFPs) used in the experiments as sources of amino acids, Whey FitPROTEIN and SPORTAMIN® BCAA 6000 (BCAA carrier) were purchased from the Russian company ACADEMIA-T and consumed once daily for three days in the dose recommended by the manufacturer (20 g for Whey FitPROTEIN and 6 g for SPORTAMIN® BCAA 6000)
The resulting total RNA of each sample was converted into complementary DNA for further analysis on an amplifier using a set of reagents for reverse transcription and a thermostat
Summary
The world market for health-improving, functional and sports food products is growing steadily, especially in Western countries. Social and moral damage is important when, under the influence of advertising, a consumer acquires an empty shell In their composition, SFPs are analogs of multicomponent drugs, having an active principle represented by several ingredients. It seems to us that the current state of biomedical science in combination with digital technologies allows us to propose new approaches to confirming the effectiveness of SFPs, including at the level of individual consumption. One of these approaches has received experimental confirmation, the results of which are presented in this article
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