Opportunities of complex hepatosis therapy in cattle

Abstract

The paper discusses the possibility of using a comprehensive treatment regimen for hepatosis in postpartum cows with the help of preparations with various mechanisms of hepatoprotective and anti-toxic effects. It was proved that enteral administration of Thionontrit-S against the background of intramuscular administration of Livazen to cows with clinical signs of hepatosis has a positive effect on the course of the disease and the recovery timing of animals. The use of a complex treatment regimen contributes to the manifestation of positive dynamics of the main hepatosis syndromes - hepatocellular insufficiency and impaired hepatocyte integrity, which is manifested by an increase in the level of total protein by 8.1%, albumin - by 20.9%, glucose - by 31.6%, triglycerides - by 21.4% and cholesterol - by 27.5% in comparison with the basic treatment. The use of Thionontrit-S as part of the complex treatment of bovine hepatosis made it possible to reduce the activity of the inflammatory process in the liver, which was manifested by a decrease in enzyme activity: AST - by 47.5%, ALT - by 19.9%, alkaline phosphatase - by 1.59 times, and correction of the mineral component of blood serum.