Abstract
The number of studies aimed at proving the prebiotic properties of certain substances or compositions has been actively increasing, which has led to a large accumulation of scientific information that is fragmented and not systematized. Moreover, a number of criteria have been applied in these studies. The lack of an accessible and convenient information space to compare the obtained results seems to hold back not only scientific development, but also practical development in this field. A database called the «On-line Database of Researches on Activity of Prebiotics» (ODRAP) is presented in this article, which contains information about both prebiotics and some probiotics, that were used in these researches. Currently, ODRAP collects 25 bacteria genera or their combinations, 59 bacteria species, 140 prebiotic substances, 61 prebiotic production companies, 2 methods of fermentation, and 271 analyzed articles from 2001 till 2019. To facilitate access to the database, a special Web-interface was created, which allows any user who opens the Web-page to obtain information about the features and activities of prebiotics, as well as to sort the data by species and genus of bacteria applied in tests, the chemical nature or source of prebiotics, and other parameters. The convenience of the Web-interface is that it allows access to the database, regardless of the user platform and from anywhere, via the Internet.
Highlights
The human body is a complex system consisting of about 1014 microbial cells interacting with the host [1,2]
One medium can be applied for the fermentation of different probiotics, a given probiotic can be used with different prebiotics, one cultivation method can be applied to different prebiotics, one set of metabolites can be suitable for different prebiotics, and so on [40,41]
We present the ODRAP database, which is based on the information of articles by various researchers and implemented using MS Office Access 2013 [54,55]
Summary
The human body is a complex system consisting of about 1014 microbial cells interacting with the host [1,2]. The essential role of the gut microbiota for health has generated tremendous interest in modulating its composition and metabolic function. One of these strategies is using prebiotics, which typically refers to selectively fermented non-digestible food ingredients or substances that support the growth and/or activity of health-promoting bacteria (probiotics) that colonize the gastrointestinal tract [3,4,5]. Prebiotics were defined as a non-digestible food ingredient that beneficially affects the host by selectively stimulating the growth and/or activity of one or a limited number of bacteria in the colon, and improves host health» [7]. There are number of information systems and databases which have made it possible to collect various microbiological data, among which online databases should be highlighted [8,9,10,11,12]
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