Abstract
A facile and versatile method for the synthesis of alicyclic fused pyrimidones from aminoacrylates and lactams in the presence of phosphorous oxychloride is described. The results suggest that this method is widely applicable except for cyclobutyl fused systems. This method gives better yield than the method of condensing aminopyrrolidines with the beta keto esters. Synthesis and characterization of twenty five 2-aryl-1,2-fused pyrimidone derivatives are reported. The results suggested that the methodology is widely applicable except for cyclobutyl fused systems. This method gives better yield and more versatile than the method of condensing aminopyrrolidines with the beta keto esters.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
