One‐Pot Construction of Sulfonyl Benzonorcaradienes

Abstract

One-pot stereoselective synthesis of strained sulfonyl benzonorcaradienes proceeds through base-mediated tandem annulation of o-bis-sulfonylmethyl arenes with diversified chalcones (α,β-unsaturated carbonyls) via intermolecular desulfonylative cyclopropanation, followed by intramolecular condensation. A plausible mechanism is proposed and discussed. The proposed synthetic route forms two carbon–carbon single (C–C) bonds and one carbon–carbon double (C=C) bond.