On the synthesis of cephalosporin antibiotics (III). α, β‐substituted butenolides and α,β‐substituted γ‐butyrolactones via Erlenmeyer condensations

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AbstractA synthesis of α, β‐substituted butenolides and of α, β‐substituted γ‐butyrolactones, starting from 1, 3‐dihydroxyacetone and a number of N‐acylglycines, by an Erlenmeyer condensation is described.The scope and limitations of the condensation were studied.