Abstract
Modern experiments have offered alternative interpretations on the symmetry of chiral dirhodium(II) carboxylate complexes and its relationship to their level of enantioselectivity. So, this contribution is to provide an insight on how the knowledge around the structure of these catalysts has evolved with a particular emphasis on the impact of this knowledge on enantioselectivity prediction and catalyst design.
Highlights
All models proposed to account for the enantioselectivity observed observed with different dirhodium(II)
Due to crystal packing, π‐stacking and/or existence of axial and lattice solvent molecules within the crystal unit cell, the static pose of a catalyst and its chiral ligands portrayed in its X‐ray crystal structure does not validate the adaption of the catalyst to the same conformation in solution and during catalysis
Due to crystal packing, π-stacking and/or existence of axial and lattice solvent molecules within the crystal unit cell, the static pose of a catalyst and its chiral ligands portrayed in its X-ray crystal structure does not validate the adaption of the catalyst to the same conformation in solution and during catalysis
Summary
Chiral dirhodium(II) paddlewheel complexes are among the most attractive catalysts that found a widespread application in the fields of metal-nitrene and metal-carbene transformations [1,2,3,4,5,6,7,8,9,10,11,12,13,14,15]. This immense interest originates from their exceptional ability to effectively catalyze a broad spectrum of reactions with high levels of chemo-, regio- and stereo-selectivity. Dirhodium(II)-mediated chemistry of methyl styryldiazoacetate (1) with different substrates
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
