On the Metabolism of Organic Acids byClostridium acetobutylicum

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Authors confirmatively observed the phenomena that in adequate conditions, the mode of acetone-butanol fermentation could be converted into homo-lactic acid fermentation, and that the formation of “Racemiase” (lactic acid racemiase) was intensified through the appropriate lactate level in growing culture of the bacterium, Clostridium acetobutylicum.Furthermore in this series of the papers, the possible role of “Racemiase” in the lactic acid metabolizing sequence was suggested, and the chemical properties of “Racemiase” as well as the mechanism of enzymatic racemization of lactic acid were investigated. The metabolism of several organic acids were also discussed in connection with the fermentation pathway of this organism.