Abstract

The parameter identification problem is treated for an SCP process in a tower loop bioreactor (fed batch process). The emphasis is laid on the sensors needed for proper identification of the unknown four parameters in the given model. In particular the following three questions are solved: a)Which types of measurements must be used (dissolved oxygen in liquid phase of the reactor - cell mass - outlet gas analysis), b) how many sensors for dissolved oxygen must be installed, c) where should these sensors be posed along the reactor column? The calculations are based on evaluations of the Fisher information matrix. Identification results are given, based on measurements taken at a bench-scale plant.

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