Abstract
An on-line intelligent measurement system based on H + -ISFET and penicillinase FET is described. The system consists of a sampling system, a diluting system, a liquor store, a monitoring cell, a series of tubing pumps for driving the sample, a testing circuit and a control circuit. The technology of differential measurement, temperature and drift compensation as well as the calibration curve of the piece-wise fitting method are applied to the system. The measurement system can control a complete process of sampling, calibrating, cleaning, testing, and calculating. The process is controlled by a microprocessor. The real-time testing results based on H + -ISFET and penicillinase FET are presented. The testing results of a pH 6.86 buffer solution during 15 h based on H + -ISFET are: the standard deviation = pH 0.008, the coefficient of variation = 0.1%. The correlation coefficient to test a series of buffer pH values is r = 0.9999, the analysis frequency = 60 samples per hour. The results to test a series of penicillin standard solutions based on the penicillinase FET are: correlation coefficient = 0.9999, the test cycle is about 3 min. This system has been experimentally justified in a pharmacy factory.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call