Abstract
Background: Host modulatory therapy has been proposed as a treatment for periodontal diseases. Omega-3 polyunsaturated fatty acids (PUFAs), including docosahexaenoic acid (DHA)and eicosapentaenoic acid (EPA) , were shown to have therapeutic anti-inflammatory and protective actions in inflammatory diseases including periodontitis. Aim of study: To test the effect of Adjunctive treatment of chronic periodontitis with daily dietary supplementation with omega-3 fatty acid Material & Method: Fifty patients with chronic periodontitis were enrolled in this study, in a double blind clinical study . the control group was treated with scaling and root planning(SRP) and a placebo, where as the study group was treated with SRP followed by dietary supplementation of Omega-3 ( 1000 mg EPA+DHA) for three months . plaque and gingival index, bleeding on probing , probing depth were recorded at base line , after 1 and 3 months after treatment. Results: the omega-3 group had highly significant lower scores for Plaque index(P<0.001), gingival index(GI P< 0.001) and significant lower scores for the probing pocket at all examination than did the control group. At first visit mean PLI scores was 1.94 after three months it was 0.73. for the GI it was 1.98 at first visit ,after three months it was 0.733.for PPD it was 4.79 was reduced to 3.05 after three months. Conclusion: The results of this study suggest that dietary supplementation with omega-3 may provide a sustainable , low cost intervention to augment periodontal therapy. Key word: omega-3 , fish oil , periodontal disease.
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