Abstract
Introduction: The Nonalcoholic Fatty Liver Disease (NAFLD) is one of the major forms of chronic liver disease. NAFLD is considered the hepatic manifestation of the metabolic syndrome, thus, a new and more appropriate nomenclature has been suggested: Metabolic Associated Fatty Liver Disease (MAFLD). An imbalance of copper homeostasis has been described in the progression of NAFLD/MAFLD toward Nonalcoholic steatohepatitis (NASH), or Metabolic-associated Steatohepatitis (MASH).
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