Abstract
This chapter consists of asymmetric hydroamination and hydroalkoxylation of electron-deficient olefins, namely asymmetric aza-Michael reactions (aza-MRs) and oxa-Michael reactions (oxa-MRs). Both reactions are organized by intermolecular reactions, intramolecular reactions, and tandem reactions, as much as possible in the order reported. The reactions are classified by the nucleophile employed, and then subdivided by the electrophiles with which they have been reacted. The choice of nucleophiles, Michael acceptors, and chiral catalysts is among the most important factors for achieving high yields and enantioselectivities. Owing to the large number of publications, this chapter does not report details for all aspects of the reaction.
Published Version
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