Abstract
Few decisions have had such a far-reaching effect on the development and production of biological products as that made in 1954 by the Armed Forces Epidemiological Board. It was at that point that a decision had to be made regarding the use of HeLa cells as the substrate for an experimental adenovirus vaccine. Because HeLa cells were rejected in favour of ‘normal cells’, a philosophy emerged which equated anything other than primary cell cultures from normal tissues of normal animals as dangerous and unacceptable. It was a philosophy which probably made sense at the time, and which had the general support of the biomedical community. However, once it became established as a standard of practice, any suggestion to depart from that position was met with significant obstacles as exemplified by the diploid cell line saga.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
