Abstract
The use of off-resonance methods in interventional MRI may be valuable since active devices that provide positive signal enhancements are currently not approved for human use. This study investigated the capacity of a low flip angle steady-state free precession (FLAPS) method for generating off-resonance positive contrast surrounding a susceptibility-shifted endomyocardial Stiletto catheter in excised swine hearts and in live swine. Consistent with theory, discernable positive contrast surrounding the interventional device was visualized under ex-vivo (CNR of 24 ± 2.1 in the left ventricular (LV) chamber and 18 ± 2.7 in LV myocardium) and in-vivo conditions (CNR of 22 ± 3.9 in aorta, 16 ± 4.1 in the LV chamber and 13 ± 0.9 in LV myocardium). The findings show that off-resonance imaging with the FLAPS method may be used for passive device visualization with positive contrast. Further studies are necessary prior to clinical translation.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
