Abstract
Ocular surface squamous neoplasia (OSSN) are important because they mimic many common indolent lesions like pterygium and have a potential for causing ocular and systemic morbidity and mortality. Ultraviolet-B light and human papilloma viruses have been proposed as major risk factors in the etiopathogensis. Anterior segment optical coherence tomography, ultrasonic biomicroscopy and impression cytology have been added recently as non-surgical tools for diagnosis and management. The treatment includes surgery as mainstay with Mitomycin-C and cryotherapy as adjuvant therapy. Recently Interferons (IFN) as well as pegylated IFNs are regularly being used in a select subsets of OSSN for treatment. Del J Ophthalmol 2012;23(2):89-96.
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