Abstract
Immunologic factors play the most important part in idiopathic thrombocytopenic purpura Viral agents also cause the disease by this way Human parvovirus B19 has been shown to play a part as a viral etiologic agent in thrombocytopenia In the present study 29 idiopathic thrombocytopenic purpura patients were examined Parvovirus B1 9 IgM was present in 4 of 29 patients 13 7 and parvovirus B19 IgG positivity in 13 44 8 In the control group parvovirus B19 IgG positivity was 43 In 4 patients with parvovirus B19 IgM positivity relapse and chronic idiopathic thrombocytopenic purpura was not observed after treatment Nine patients with negative parvovirus B19 IgM developed chronic idiopathic thrombocytopenic purpura in the follow up period With respect to their response to treatment the rate of development a chronic situation in patients with parvovirus B1 9 IgM positivity was significantly less than those with parvovirus B19 IgM negativity As a result the positivity of parvovirus B19 observed in our idiopathic thrombocytopenic purpura patients was correlated with similar studies and it was emphasized that parvovirus B1 9 had a role 50 that idiopathic thrombocytopenic purpura caused by parvovirus B19 gave better response to treatment Key words: Idiopathic thrombocytopenic purpura thrombocytopenia parvovirus B19
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