OBTAINING OF TiO2-SiO2-P2O5/ZnO COMPOSITES, INVESTIGATION OF THEIR PROPERTIES AND POSSIBILITY OF APPLICATION AS A BIOMATERIAL

Abstract

In modern implantology composites based on various inorganic and polymeric materials are promising, which are able to provide strong adhesion with tissues in contact with the implanted material and stimulate the growth of new tissue on the implant surface. In the work macroporous cationite Tokem-250 with high selectivity to Zn2+ ions was used as a matrix, which makes it possible to use it in the development of biomaterials. Zinc has a direct stimulating effect on bone tissue formation and has antibacterial properties. For the cationite Tokem-250 based on acryl-divinylbenzene matrix the values of total exchange capacity and sorption capacity in relation to Zn2+ ion were determined. Total exchange capacity of cationite Tokem-250 is 10.35 mmol∙ekv/g, sorption capacity is 73% of the total exchange capacity and is equal to 7.58 mmol∙ekv/g. Spherical composites TiO2-SiO2-P2O5/ZnO on the basis of cationite Tokem-250 were synthesized from alcohol solutions by sol-gel method. For obtaining spherical composite the conditions of heat treatment of samples are established: drying at 60 ºC and step annealing at 150, 250, 350 ºC for 30 min at each temperature step, at 600 ºC - 6 h, at 800 ºC - 1 h. The obtained composites have the ability to precipitate and mineralize calcium-phosphates on their surface in biological media, because they have homogeneous structure with uniform distribution of elements on the surface, mesoporous structure with pore size from 5 to 12 nm and the presence of active centers (Si4+, Ti4+) on the surface of composites. The use of polyvinyl alcohol as a binder does not prevent the formation of an apatite-like layer. For citation: Tkachuk V.A., Lyutova E.S., Buzaev A.A., Borilo L.P., Spivakova L.N. Obtaining of TiO2-SiO2-P2O5/ZnO composites, investigation of their properties and possibility of application as a biomaterial. ChemChemTech [Izv. Vyssh. Uchebn. Zaved. Khim. Khim. Tekhnol.]. 2024. V. 67. N 5. P. 70-76. DOI: 10.6060/ivkkt.20246705.6953.