Obstructive Sleep Apnea during Pregnancy and the Morbidity Outcome

Abstract

Obstructive Sleep Apnea during Pregnancy and the Morbidity Outcome Background: There is an increasing concern that obstructive sleep apnea is a risk factor of a poor pregnancy outcome. Our research design used polysomnography, which gives an objective measurement in defining obstructive sleep apnea in non-high risk pregnancy. This study was carried out to measure the prevalence of obstructive sleep apnea in pregnancy and show whether obstructive sleep apnea is a risk factor of poor pregnancy outcome. Methods: A prospective cohort study had been carried out at Chiang Mai University Hospital. 50 pregnancy women who received antenatal care at Chiang-Mai University hospital were included in the study. All subjects were assessed by physical examination and polysomnography at GA 28th-32nd weeks and were followed until the end of the pregnancy to see the difference in poor pregnancy outcomes in the obstructive sleep apnea and non-obstructive sleep apnea group. Results: The prevalence of obstructive sleep apnea in pregnancy was 12%. Obstructive sleep apnea related to overall more poor pregnancy outcomes (RR=7.33(2.45-21.86), p=0.004), more preterm labor (RR=22.0(2.70-178.99), p-0.004), more preeclampsia (p=0.012). Conclusions: Obstructive sleep apnea was a high risk in pregnancy and should be screened for with multidisciplinary team cooperation, to establish the diagnosis and treatment to enhance maternal and child health