Abstract

SummaryThirty‐five years ago we commenced a study on the causation and prevention of thyroid disease in this country.The first reports of endemic goitre were made in 1888, and in 1920 the relationship to low iodine environment was reported. After some preliminary failures prophylaxis with iodized salt was successful in 1940. The goitrogenic factor in certain foodstuffs was studied in 1928 and subsequently, and this work was the forerunner of the therapeutic use of thiouracil.Currently we are studying thyroid function by means of radioactive iodine, and experience in its use in diagnosis and treatment is presented.While progress has been made, more questions have been raised than answered. It is indeed true that “Knowledge is proud that he knows so much, while Wisdom is humble that he knows no more”.

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