OBSERVATIONS ON RELAPSES IN PERNICIOUS ANEMIA

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Article1 February 1949OBSERVATIONS ON RELAPSES IN PERNICIOUS ANEMIAEDGAR JONES, M.D., F.A.C.P., CLIFFORD C. TILLMAN, M.D., WILLIAM J. DARBY, M.D.EDGAR JONES, M.D., F.A.C.P.Search for more papers by this author, CLIFFORD C. TILLMAN, M.D.Search for more papers by this author, WILLIAM J. DARBY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-30-2-374 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn the fall of 1945 and winter of 1946 liver extract was discontinued on 12 patients with pernicious anemia who were attending the out-patient department of Vanderbilt University Hospital. There were seven males and five females in the group. Two of the men were Negroes. None had evidence of neurological disease. All of these patients were regarded as being adequately treated. The total amount of liver extract which had been injected during the year prior to withdrawal of treatment varied from 420 to 1020 units and had been given at intervals of three to four weeks in the majority of...Bibliography1. STRAUSSPOHLE MBFJ: The duration of remission in pernicious anemia with liver therapy, Jr. Am. Med. Assoc., 1940, cxiv, 1318. Google Scholar2. FARQUHARSONBORSOOKGOULDING RFHAM: Pigment metabolism and destruction of blood in Addison's (pernicious) anemia, Arch. Int. Med., 1931, xlviii, 1156. CrossrefGoogle Scholar3. WATSON CJ: Studies of urobilinogen. 1. An improved method for the quantitative estimation of urobilinogen in urine and feces, Am. Jr. Clin. Path., 1936, vi, 458. CrossrefGoogle Scholar4. HEINLEWELCH RWAD: Folic acid in pernicious anemia: failure to prevent neurologic relapse, Jr. Am. Med. Assoc., 1947, cxxxiii, 739. CrossrefGoogle Scholar5. ROSSBELDINGPAEGEL JFHBL: The development and progression of subacute combined degeneration of the spinal cord in patients with pernicious anemia treated with synthetic pteroylglutamic (folic) acid, Blood, 1948, iii, 68. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Presented at the Twenty-Ninth Annual Session of the American College of Physicians, San Francisco, California, April 20, 1948.This work was supported in part by a grant from National Vitamin Foundation, Inc. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byRelapses after interruption of cyanocobalamin therapy in patients with pernicious anemiaThe Diagnosis of Pernicious AnemiaTreatment of megaloblastic anemiasSome considerations pertaining to the proper use of supplementary vitaminsProlonged treatment of pernicious anemia with vitamin B12The Treatment of Pernicious Anemia and Other Macrocytic Anemias With Vitamin B12Vitamin Supplementation in Health and Disease 1 February 1949Volume 30, Issue 2Page: 374-380KeywordsFallsLiverOutpatientsPernicious anemia ePublished: 1 December 2008 Issue Published: 1 February 1949 PDF downloadLoading ...