Abstract
THE THYROID gland is unique in that the incidence of various forms of disease of this gland differs markedly in different localities. The lability of the thyroid in response to a variety of stimuli, particularly to the amount of iodine available to the organism, results in variations in the size and histological structure of the gland which in turn lead to distinctive pathological variations in disease. Although many reports are extant as to the incidence of various forms of thyroid disease in the urban centers of the Atlantic Coast and in the recognized goitrous regions of the Great Lakes, mid-Western Plains and the Northwest, there is little reference in the literature to thyroid disease as it occurs in the Blue Ridge Mountains of the Appalachian Range. This mountainous area is a typical goitrous region and gives rise to a moderately high incidence of goiter. We thought it of interest, therefore, to analyze the incidence of various forms of disease of the thyroid gland in this area and compare it with s...
Published Version
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