Observation on curative effect of telmisartan combined with levamlodipine besylate tablets in treatment for primary hypertension patients with Type 2 diabetes mellitus

Abstract

Objective To investigate the influence of the telmisartan combined with levamlodipine besylate tablets in treatment for the microalbuminuria of primary hypertension patients with Type 2 diabetes mellitus. Methods 219 masculine cases of primary hypertension with Type 2 diabetes mellitus patients were randomly divided into telmisartan group (control group A), levamlodipine besylate group (control group B), and telmisartan combined with levamlodipine besylate group(observation group), 73 cases for each group, three groups were treated for 24 weeks, to observe the change of 24 hours ambulatory blood pressure, glycosylated hemoglobin and 24-hour microalbuminuria before and after treatment. Results 24 weeks after treatment, the total effective rate of the observation group was 98.63%, while those of the control group A and control group B were 82.19% and 80.82% respectively, the observation group was lower than the control group A and B (P＜0.05), the blood pressure and microalbuminuria in observation group were obviously lower than those in the control group A and B (P＜0.05).Conclusion It suggested that the telmisartan combined with levamlodipine besylate tablets in treatment for the microalbuminuria of primary hypertension patients with Type 2 diabetes mellitus could effectively contrel the blood pressure, obviously reduce the microalbuminuria and protect renal function. It is worthy for primary hospitals to spread and exploitation. Key words: Primary hypertension patients with Type 2 diabetes mellitus; Telmisartan; Levamlodipine besylate tablets