Observation of montelukast combined with small dose of inhaled corticosteroid in the treatment of cough variant asthma

Abstract

Objective To study the curative effect of combing montelukast with inhaled corticosteroids in the treatment of cough variant asthma. Methods According to ＂diagnosis standard guideline for diagnosis and treatment of cough in CVA＂ ,84 cases of CVA patients were chosen and divided into the treatment group （n = 42）and the control group（ n =42）. The control group were treated with inhaled corticosteroid Budesonide. The treatment group was given monelukast based on the treatment in control group. And the clinical effects of two groups, recurrence and the lung function index were observed. Results The total efficiency of treatment of the control group was 73.8%, and the treatment group was 95.0%. The total effective rate of observation group was apparently higher than that of the control group （ X2 = 6.46, P 〈 0.05 ）. The lung function of the treatment group compared to the control group was significantly increased（t = 2. 873,P 〈 0.05 ）. Conclusion Montelukast combined with Glucocorticoid in the treatment of CVA can effectively improve the cure rate, reduce the recurrence, which can be widely used in clinical treatment. Key words: Montelukast; Glucocorticoids ; Variant asthma;