Abstract

Attention-deficit hyperactivity disorder (ADHD) is the most common neuropsychiatric disorder in schoolchildren. Several methods are available to evaluate ADHD therapeutic effects, including the Swanson, Nolan, and Pelham (SNAP) questionnaire, the Vanderbilt ADHD Diagnostic Rating Scale, and the visual analog scale. However, these scales are subjective. In this study, a piezoelectric material was applied to a medical chair to objectively evaluate the therapeutic effect of ADHD medication before and after treatment. A total of 22 patients (18 boys and 4 girls) with ADHD were enrolled. During the appointment, the patients’ movements were recorded by the piezoelectric material before being analyzed. The variance, zero-crossing rate, and high energy rate of movements were used to analyze the signal in this study. The results showed the variance, zero-crossing rate, and high energy rate in patients with ADHD all decreased significantly after 1 month of methylphenidate use. Although the hyperactivity subscales of SNAP obtained from parents and teachers demonstrated significant decreases after 1 month of medication, the reduction rate of the three aforementioned measurements decreased more than hyperactivity subscales. This suggests that the use of a smart chair equipped with a piezoelectric material is an objective and useful method for evaluating the therapeutic effects of ADHD medication.

Highlights

  • Attention-deficit hyperactivity disorder (ADHD) is one of the most common neuropsychiatric disorders, affecting 8–10% of children worldwide [1]

  • The 26 items of the SNAP-IV include the 18 ADHD symptoms (9 related to inattentiveness and 9 related to hyperactivity/impulsiveness) and the 8 oppositional defiant disorder symptoms specified in the DSM-IV

  • We found that the variance, zero-crossing rate, and high energy rate siggnniiffiiccaannttllyy ddeeccrreeaasseeddininppataiteinentstswwithithADAHDHDDaftaefrtetretartematemntenwtitwhimthemtheytlhpyhlepnhidenatide,aaten, AanDAHDDHmDemdiecdatiicoanti.oTnh. uTsh,utsh,ethveavriaarniacne,cez,ezreor-ocr-corsossinsigngrartaet,ea, nanddhhigighheenneerrggyyrraattee mmay be useffuull and objective markers for evaluating the therapeutic effects of ADHD medication in patients with ADHD

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Summary

Introduction

Attention-deficit hyperactivity disorder (ADHD) is one of the most common neuropsychiatric disorders, affecting 8–10% of children worldwide [1]. Several methods are available for evaluating the therapeutic effects of ADHD medication, including the Swanson, Nolan, and Pelham (SNAP) questionnaire [5], Vanderbilt ADHD Diagnostic Rating Scale [6], and visual analog scales [7]. These scales are scored by the parents or teachers of the patients, and this can lead to subjective bias during evaluation. An objective method of measuring therapeutic effects is essential for monitoring the treatment effects of ADHD

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