Obesity and periodontal disease – An overview

R Vijayalakshmi,Jaideep Mahendra,Sruthi Srinivasan,Thamaraiselvan Thamaraiselvan,Burnice Nalina Kumari

doi:10.18231/j.ijpi.2020.001

R Vijayalakshmi, Jaideep Mahendra + Show 3 more

Open Access

https://doi.org/10.18231/j.ijpi.2020.001

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Abstract

Obesity and periodontal disease – An overview - IJPI- Print ISSN No: - 2581-9836 Online ISSN No:- 2457-0087 Article DOI No:- 10.18231/j.ijpi.2020.001, IP International Journal of Periodontology and Implantology-IP Int J Periodontol Implantol

Highlights

The World Health Organization (WHO) defines overweight and obesity as “abnormal or excessive fat accumulation that presents a risk to health.[1]
Obesity is a condition where the utilization and distribution of nutrients and energy status poses to be a challenge at cell and organism levels
Obesity is often associated with increased lipid and blood glucose levels, which may have deleterious consequences for the host response leading to alterations in T cells and monocytes/macrophages, as well as an increased cytokine production

Summary

Introduction

The World Health Organization (WHO) defines overweight and obesity as “abnormal or excessive fat accumulation that presents a risk to health.[1]. The levels of leptin are known to increase since there is resistance to leptin at receptor level Visfatin It is the most recently identified adipocytokine produced by visceral adipose tissue. Resistin originates from inflammatory cells in fatty tissues During inflammation, it acts on adipocytes and causes insulin resistance. C-reactive protein The levels are known to increase in obese individuals It is a risk factor for development of cardio-vascular disease and type –II diabetes mellitus. Genco et al analyzed National Health and Nutrition Examination Survey (NHANES III) data and demonstrated that BMI was positively correlated with the severity of periodontal attachment loss; they found that this relationship is modulated by insulin resistance.[21] The underlying biological mechanisms for the association of obesity with periodontitis are not well known; adipose-tissue–derived cytokines and hormones may play a key role.

Impaired tissue healing

Findings

Conclusion