O12-2 The epidemiology of rare cancers from National Cancer Registry in Japan

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Rare cancers are defined as malignancies with an incidence of less than 6 per 100,000 people per year. Approximately 200 different malignancies are categorized as rare cancers, and 15% of all malignancies are represented by rare cancers in Japan. However, epidemiological information, including the incidents, distribution of age, sex, region, were mainly estimated by hospital-based cancer registry and organ-specific cancer registries, and comprehensive actual numbers were insufficient. Especially in rare cancers, the reliability of the estimated epidemiological data may be unstable, because of rarity of disease.