Abstract
Introduction - Ankylosing spondylitis (AS) or radiographic ankylosing spondylitis is an axial spondyloarthritis with a male predominance, whose symptoms include low back pain associated with morning stiffness that can progress to ankylosis. Its inflammatory etiology is associated with structural changes, which can influence the clinical condition, functionality and response to treatment. Objective: To study body composition and its influence on the inflammatory parameters of AS according to sex. Method: Sixty-seven patients with AS had lean and fat body mass assessed by bioimpedance and Body Mass Index (BMI) assessment. Disease activity was measured by ASDAS PCR and physical function by BASFI. Result: All patients had fat mass above predicted and lean mass below predicted, and the majority had a BMI above normal. There was a positive correlation between BMI and ASDAS PCR only in men, with no correlation in women. Conclusion: Obesity contributed to the increase in inflammatory activity parameters in male AS patients.
Published Version
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