O.012 Normal human oral fibroblasts and keratinocytes obtained by means of tissular engineering

Abstract

Reconstruction of very large lip defects is almost always difficult, simply because of the nature of the defect. Compromises are therefore often necessary. The best reconstructions are usually achieved using remaining lip elements and by restoring the continuity of the orbicularis oris muscle so that lip incompetence is minimized. One useful approach is to use a combination of Karapandzic and Abbe flaps to maximize redistribution of the remaining lip. With careful technique, acceptable results can often be achieved. If this is not possible, distant tissue can be used, but lip incompetence and drooling may result.