Nutritional assessment for 891 patients with common cancer in a cancer hospital of southwest China.

Abstract

e23280 Background: Malnutrition is a problem affecting tumor patients greatly. To investigate the nutritional status of hospitalized patients with common malignant tumor in a cancer hospital of Southwest China. Methods: From April 2017 to May 2021, we enrolled 891 patients with cancer hospitalized for treatment in Chongqing university Cancer Hospital. These patients were diagnosed with one of the following 16 different types of malignant tumors: lung cancer, gastric cancer, liver cancer, colorectal cancer, breast cancer, esophageal cancer, cervical cancer, endometrial cancer, nasopharyngeal carcinoma, malignant lymphoma, leukemia, pancreatic cancer, ovarian cancer, prostate cancer, bladder cancer and brain tumor. Patient-generated subjective global assessment (PG-SGA), anthropometric measurements, and laboratory examination were used to evaluate the nutritional risk or nutritional status.Cancer pain status were assessed with the Numerical Rating Scale (NRS). We also investigated the nutritional therapy of these cancer patients. Results: According to the PG-SGA score, 48.7% (434/891) of the cancer patients were severe malnutrition (PG-SGA≥9), 31.2% (312/891) were moderate malnutrition (8≥PG-SGA≥4), 14.7% (131/891) were mild malnutrition (PG-SGA 2~3), and only 5.4% (48/891) patients were no malnutrition (PG-SGA 0~1) . The rate of malnutrition for gastrointestinal cancer patients is higher than Nongastrointestinal cancer patients (67.3% vs. 44.6%, χ2 = 31.48, P < 0.001). Multiple linear regression analysis, PG-SGA scores and body mass index (P < 0.001), serum total protein(P < 0.001), hemoglobin serum(P < 0.001), albumin (P < 0.001), prealbumin ( P< 0.001), calf circumference (left side, P = 0.001) were correlated. Age(≥65 years), albumin( < 40g/L), prealbumin ( < 150mg/L) and cancer pain (NRS≥4) are the risk factors of severe malnutrition. However, only 26.8% (200/746) of all the moderately and severely malnourished patients received nutritional therapy. Conclusions: 94.6% of the common malignant tumor patients enrolled in the present study were malnutrition. PG-SGA is an effective tool to assess malnutrition in cancer patients, it is recommended to conduct routine assessment of cancer patients at the beginning of admission. Nutritional therapy of malignant tumor patients with malnutrition is very low. Suggestions for patients with malignant tumor after admission nutritional risk screening, and comprehensive nutritional evaluation, including PG-SGA score, and to give the right nutritional therapy.