Abstract

BackgroundMalnutrition as a result of insufficient intake or uptake of nutrition leads to increasing rate of chronic diseases such as stroke. Stroke is one of the most common causes of death in western countries and its increasing trend has attracted lots of attention. In this regard, it seems logical to focus on modifiable risk factors such as nutrition, in order to reduce the resulting complications. Accordingly, this study aimed at evaluating nutrition status of stroke patients to estimate its relationship with clinical outcomes of stroke.MethodsIn the present cross-sectional study, 349 patients were recruited. Nutrition assessment was performed using Patient-Generated Subjective Global Assessment (PG-SGA). In addition, National Institutes of Health Stroke Scale (NIHSS), modified Rankin Scale (mRS), and biochemical tests were performed.ResultsOur findings elucidated a significant positive correlation of mRS with PG-SGA and consciousness score, as well as a negative correlation with BMI, calf circumference, mid-arm circumference, and triceps skinfold at admission time (P ≤ 0.002). Moreover, a direct correlation was found between mRS and PG-SGA and consciousness score at discharge time (P ≤ 0.001). In contrast, an inverse correlation was established between mRS and mid-arm circumference (P = 0.02). Furthermore, univariate analysis indicated significant associations between mRS ≥ 3 and age (OR: 1.02; 95%CI: 1.00–1.04), PG-SGA (OR: 1.08; 95%CI: 1.03–1.13), NIHSS (OR: 1.04; 95%CI: 1.02–1.07), dysphagia (OR: 1.69; 95%CI: 1.03–2.77), consciousness (OR: 1.48; 95%CI: 1.07–2.04), and mid-arm circumference (OR: 0.95; 95%CI: 0.90–1.00). In addition, these associations remained significant in multivariate analysis for PG-SGA (OR: 1.07; 95%CI: 1.00–1.13) and NIHSS (OR: 1.04; 95%CI: 1.01–1.07).ConclusionThis study revealed a positive correlation between mRS and consciousness status and PG-SGA score, as well as a negative one between mRS and MAC at discharge time.

Highlights

  • Malnutrition as a result of insufficient intake or uptake of nutrition leads to increasing rate of chronic diseases such as stroke

  • Stroke is one of the most common causes of death in western countries and regarding its increasing trend, it is required to focus on modifiable risk factors to prevent its prevalence

  • This study aimed to evaluate nutritional status of stroke patients at admission time and identified malnourished patients to estimate its relationship with clinical outcomes of stroke

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Summary

Introduction

Malnutrition as a result of insufficient intake or uptake of nutrition leads to increasing rate of chronic diseases such as stroke. Stroke is one of the most common causes of death in western countries and its increasing trend has attracted lots of attention In this regard, it seems logical to focus on modifiable risk factors such as nutrition, in order to reduce the resulting complications. There is a large body of data supporting the concept that nutrition evaluation in hospitalized stroke patients is critical and would give us a starting point to look at this issue as a priority [4, 5] To this end, several tools have been developed to identify patients at risk of malnutrition and consider proper nutritional interventions. The objective one is based on the hematological and biochemical parameters In this regard, the Patient-Generated Subjective Global Assessment (PG-SGA) is a widely used subjective nutritional screening tool including assessment of body weight, food intake, symptoms, relationship between disease and nutritional requirement, metabolism requirement, and physical examination [6, 7]. This study aimed to evaluate nutritional status of stroke patients at admission time and identified malnourished patients to estimate its relationship with clinical outcomes of stroke

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