Nursing care of patients with acute radiation-induced oral mucositis treated with Shenmai Decoction plus Gene Time

Abstract

Objective To explore the effect and nursing care of Shenmai Decoction plus Gene Time （ recombinant human epidermal growth factor ） on the treatment of radiation oral mucositis .Methods Totals of 80 head-and-neck cancer patients receiving radiotherapy were randomly divided into treatment group （ n=40 ） and control group （n=40）.The treatment group was treated with Shenmai Decoction in combination with Gene Time spraying on the irradiated oral mucosa after cleaned , while the control group was treated only with Gene Time.The course of treatment of both groups was 7 weeks.The total curative effect of two groups were observed and the nursing methods were summarized .Results As the increasing dose of radiotherapy , the incidence rates ofⅢ-degree and Ⅳ-degree oral mucositis were increased significantly in the two groups （15.0% vs 25.0%, 25.0%vs 40.0%;χ^2=13.08, 10.31, respectively;P<0.05）.However, the incidence rate of Ⅲ-degree andⅣ-degree oral mucositis of treatment group was significantly lower than that of control group （ 15 .0% vs 25.0%, 25.0%vs 40.0%;χ^2=9.21,14.39, respectively;P〈0.05）.And total effective rate of treatment group was significantly better than that of control group （ 87.5% vs 85.0%; χ^2=0.105, P〉0.05 ）. Conclusions Shenmai Decoction plus Gene Time can reduce the incidence of radioactive oral mucositis and significantly enhance the curative effect .Nursing interventions can improve the rehabilitation of oral mucositis patients. Key words: Nursing; Radioactive mucositis; Shenmai decoction; ; Gene Time（Recombinant human Epidermal growth factor）