Abstract
Limited evidence exists on effective interventions to improve knowledge of preventive medications in patients with chronic diseases, such as stroke. We investigated the effectiveness of a nurse-led intervention, where a component was to improve knowledge of prevention medications, in patients with stroke or transient ischemic attack (TIA). Prospective sub-study of the Shared Team Approach between Nurses and Doctors for Improved Risk Factor Management, a randomized controlled trial of risk factor management. We recruited patients aged ≥18 years and hospitalized for stroke/TIA. The intervention comprised an individualized management program, involving nurse-led education, and management plan with medical specialist oversight. The outcome, participants' knowledge of secondary prevention medications at 12 months, was assessed using questionnaires. A score of ≥5 was considered as good knowledge. Effectiveness of the intervention on knowledge of medications was determined using logistic regression. Between May 2014 and January 2015, 142 consecutive participants from the main trial were included in this sub-study, 64 to usual care and 78 to the intervention (median age 68.9 years, 68% males, and 79% ischemic stroke). In multivariable analyses, we found no significant difference between intervention groups in knowledge of medications. Factors independently associated with good knowledge (score ≥5) at 12 months included higher socioeconomic position (OR 4.79, 95% CI 1.76, 13.07), greater functional ability (OR 1.69, 95% CI 1.17, 2.45), being married/living with a partner (OR 3.12, 95% CI 1.10, 8.87), and using instructions on pill bottle/package as an administration aid (OR 4.82, 95% CI 1.76, 13.22). Being aged ≥65 years was associated with poorer knowledge of medications (OR 0.24, 95% CI 0.08, 0.71), while knowledge was worse among those taking three medications (OR 0.15, 95% CI 0.03, 0.66) or ≥4 medications (OR 0.09, 95% CI 0.02, 0.44), when compared to participants taking fewer (≤2) prevention medications. There was no evidence that the nurse-led intervention was effective for improving knowledge of secondary prevention medications in patients with stroke/TIA at 12 months. However, older patients and those taking more medications should be particularly targeted for more intensive education. Australian New Zealand Clinical Trials Registry (ACTRN12688000166370).
Highlights
Use of evidence-based pharmacological therapies is a recognized strategy for controlling vascular risk factors in patients with stroke [1,2,3]
To empower patients with chronic diseases, it is recommended that education and counseling on use of medications is initiated during their acute hospital stay [10]
We investigated the effectiveness of a nurse-led individualized management program for improving knowledge of secondary prevention medications in patients with stroke or transient ischemic attack (TIA)
Summary
Use of evidence-based pharmacological therapies is a recognized strategy for controlling vascular risk factors in patients with stroke [1,2,3]. In patients with chronic diseases, such as stroke, a major factor associated with adherence to medications is adequate knowledge regarding the often complex medication regimen [4]. This includes knowing the name, administration, handling, and potential side effects of the medications [5]. To empower patients with chronic diseases, it is recommended that education and counseling on use of medications is initiated during their acute hospital stay [10]. This is usually complemented by long-term interventions to facilitate effective use of medications post-discharge [11]. Primary care providers, including nurses and pharmacists, have important roles in implementing these strategies
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