Abstract
Abstract Dual-frequency ultrasound methods can be used to detect microbubbles in biological tissues, and bubble pulsation under acoustic waves is significant for the detection results. In this study, the dynamic equation of bubbles in viscoelastic media was numerically solved and the instantaneous radius of bubbles under single-frequency and dual-frequency ultrasound were compared. The maximum values of the bubble radii at different incident frequencies were calculated. In addition, the effects of the bubble equilibrium radius and the shear modulus of the surrounding medium on the bubble oscillations are investigated. The results show that the bubble pulsation under dual-frequency ultrasound is more complex than that under single-frequency. The elasticity of the media affects the resonant frequency of the bubble and the frequency increases with the shear modulus. When the frequency of the incident wave is equivalent to the resonant frequency of the bubble, the amplitude of the bubble oscillation radius achieves a maximum. Moreover, the spectrum of the bubble oscillation radius is correlated with both the bubble equilibrium radius and the shear modulus of the surrounding medium.
Published Version
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