Abstract

This article studies the existence and uniqueness of a weak solution of the time-fractional cancer invasion system with nonlocal diffusion operator. Existence and uniqueness results are ensured by adapting the Faedo-Galerkin method and some a priori estimates. Further, finite element numerical scheme is implemented for the considered system. Finally, various numerical computations are performed along with the convergence analysis of the scheme.

Highlights

  • In the past few decades, a large number of mathematical models have been applied for biological studies

  • Finite element methods have become popular for numerical simulations of time-fractional diffusion equations due to their good approximation and feasibility to work with any domains

  • Esen et al [36] studied the numerical solutions of time-fractional diffusion equations and diffusionwave equations using Galerkin finite element method

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Summary

INTRODUCTION

In the past few decades, a large number of mathematical models have been applied for biological studies. Finite element methods have become popular for numerical simulations of time-fractional diffusion equations due to their good approximation and feasibility to work with any domains. Esen et al [36] studied the numerical solutions of time-fractional diffusion equations and diffusionwave equations using Galerkin finite element method. Jin et al [29] analyzed the numerical solutions of multiple time-fractional derivative using the Galerkin finite element method. Fractional models are proposed and used in chemical reactions, propagation phenomena, transport systems, pattern formation processes and spatiotemporal distribution of species [41,42,43,44,45] and references therein In this connection, we are interested to study and analyze the time-fractional cancer invasion model with nonlocal diffusion operator.

EXISTENCE AND UNIQUENESS
FINITE ELEMENT SCHEME
Finite Element Semi-discretization
NUMERICAL EXPERIMENT
Convergence Study
Numerical Results and Discussion
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