Abstract
Initiation, growth, and rupture of cerebral aneurysms are caused by hemodynamic factors. It is extensively accepted that the cerebral aneurysm wall is assumed to be rigid using computational fluid dynamics (CFD). Furthermore, fluid-structure interactions have been recently applied for simulation of an elastic cerebral aneurysm model. Herein, we examined cerebral aneurysm hemodynamics in a realistic moving boundary deformation model based on 4-dimensional computed tomographic angiography (4D-CTA) obtained by high time-resolution using numerical simulation. The aneurysm of the realistic moving deformation model based on 4D-CTA at each phase was constructed. The effect of small wall deformation on hemodynamic characteristics might be interested. So, four hemodynamic factors (wall shear stress, wall shear stress divergence, oscillatory shear index and residual residence time) were determined from the numerical simulation, and their behaviors were assessed in the basilar bifurcation aneurysm.
Highlights
We examined cerebral aneurysm hemodynamics in a realistic moving boundary deformation model based on 4-dimensional computed tomographic angiography (4D-CTA) obtained by high time-resolution using numerical simulation
Four hemodynamic factors were determined from the numerical simulation, and their behaviors were assessed in the basilar bifurcation aneurysm
Hemodynamic factors such as the wallshear stress (WSS), the studies have examined the hemodynamics of cerebral aneurysms using numerical simulation to predict their growth and rupture
Summary
Hemodynamic factors such as the wallshear stress (WSS), the studies have examined the hemodynamics of cerebral aneurysms using numerical simulation to predict their growth and rupture. To reproduce the wall movement under cardiac cycle, fluid-structure interaction simulation has been recently applied for the deformation of an elastic cerebral aneurysm model [5] [6] [7]. It is still difficult to reproduce the wall deformation of the aneurysm wall in pulsatile flow. Torii et al reported that there is significant difference of WSS distribution between rigid-wall and elastic-wall simulation. In the previous study [8], the influence of wall motion on wall shear stress is estimated by the similar method to the present study and there is small influence of wall motion on wall shear stress
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