Abstract

Exploiting acoustic streaming effects for microfluidic devices has been proven to be important for cell, microparticle and fluid manipulation in many fields such as, biomedical engineering, medical diagnostic devices, cell studies and chemistry. Acoustic streaming is used in acoustofluidic systems for directing and sorting microparticles as well as mixing and pumping fluids. To understand the underlying physics of such acoustofluidic systems and thus use them more efficiently in practical setups, computational modelling is critically needed. Although some work has been done to numerically model acoustofluidic systems, there are few studies to evaluate the capability and accuracy of different numerical schemes for analysing this complex multi-physics problem and to be directly validated by experiments. This paper aims to investigate the acoustic streaming effects caused by surface acoustic waves in a microchannel flow by using two different computational approaches to model the acoustic effects in three dimensions. In the first approach, we model the whole acoustic field caused by the oscillating lower wall. Here, the acoustic streaming effects were directly calculated from the density and velocity fields caused by the acoustic field. In the second approach, a low fidelity model is employed to capture the effects of acoustic streaming without modelling the acoustic field itself. In this approach, we substituted the velocity of a one-dimensional attenuating wave in the acoustic streaming force formula, and calculated the acoustic streaming force without using the density and velocity caused by the acoustic field. Both the computational methods are then validated by the results obtained from microflow experiments. The results from the second approach are in reasonable agreement with experiments while being more efficient in terms of computational cost. On the contrary, the first approach, while being computationally more expensive, allows to estimate the pressure field resulting from acoustic waves and thus predicts the dynamic behaviour of microparticles more accurately. Results suggest that the first approach is best to use for analysing the mechanism of microparticle and fluid manipulation in microfluidic devices.

Highlights

  • Integrating acoustics technologies such as surface acoustic wave (SAW) devices into microfluidic setups (often called.International Journal of Engineering Science 169 (2021) 103563 acoustofluidics) to manipulate and control fluid and microparticles/droplets/cells has become one of the most popular areas of microfluidics research in recent years

  • For the second approach, the trend for the z-velocity is reversed in the acoustic field

  • Effects of acoustic streaming caused by traveling surface acoustic wave (TSAW) on fluid and microparticles in a microchannel flow is investigated using numerical simulations with two different approaches

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Summary

Introduction

Integrating acoustics technologies such as surface acoustic wave (SAW) devices into microfluidic setups (often called (http://creativecommons.org/licenses/by/4.0/).International Journal of Engineering Science 169 (2021) 103563 acoustofluidics) to manipulate and control fluid and microparticles/droplets/cells has become one of the most popular areas of microfluidics research in recent years Yeo,2011 Huang, 2019, Li & Huang, 2018, Sackmann, Fulton & Beebe, Mar 13 2014, Beebe, Mensing & Walker, 2002, Franke, Abate, Weitz & Wixforth, 2009) These acoustofluidic systems offer great potentials to design and fabricate devices to address important challenges in the fields of biomedical engineering, biology, medicine and chemistry (Sackmann, Fulton & Beebe, Mar 13 2014, Beebe, Mensing & Walker, 2002, Ding et al, 2013, Schmid, Weitz & Franke, 2014, Chen, Toh, Chai & Yang, 2004). The advantages of using SAW devices as a part of microfluidic systems are their simple planar design, small size, efficiency and low cost. These devices offer reliable, precise and controllable manipulation with high biocompatibility in non-invasive and contact-free manner (Whitesides, 2006, Ding et al, 2013, Wang et al, 2017)

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