Abstract
Phosphoramidite building blocks related to the four canonical DNA constituents and oligonucleotides with octadiynyl side chains ( 5b – 8b ) or dipropargyl ether residues ( 5c ) were synthesized. Nucleosides and oligonucleotides were functionalized at the terminal triple bonds employing the Huisgen-Sharpless cycloaddition “click reaction."
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