Abstract
Pigmented rabbit conjunctival epithelium is capable of secreting fluid at a rate of 4.3 ± 0.2 µl/hr/cm2.1 Active chloride secretion across the epithelium, which in the case of conjunctiva is modulated by second messengers such as cAMP,2 Ca2+,2 protein kinase C (PKC),2,3 and purine and pyrimidine nucleotides,4 is proposed to be a major driving force for this vectorial fluid movement.5 Several of these second messengers also stimulate fluid secretion across the corneal epithelium,6 retinal pigment epithelium,7 and tracheal epithelium.8 Further, we have reported previously that 8Br-cAMP is an efficient stimulant to fluid secretion in the pigmented rabbit conjunctiva.1 KeywordsOcular SurfaceWear TimeKinin ActivityHereditary AngioedemaContact Lens WearThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call