Abstract

Ion current through individual pores in track-etched polyethyleneterephthalate filters can have the following properties which are shared by a number of biological ion channels: 1. 1) selectivity for cations over anions, or vice versa depending on the surface charge of the filter and the diameter of the pore; 2. 2) fluctuations between high- and low-conductance states; 3. 3) inhibition by protons and divalent cations with efficacy H + > Zn 2+ > Ca 2+ ∼ Mg 2+. Pore topography in differing states can be imaged by scanning probe microscopy. We conclude that track-etched filters provide a useful model system for studying the physical and chemical basis for some of the characteristic behaviour of biological channels.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.