Abstract
Abstract The number of kinds of DNA-like RNA transcribed in nuclei of developing Rana pipiens embryos decreases from the early neurula to the larval stage. Approx. 16% of the DNA hybridized with RNA extracted from nuclei of early neurulae while only 2% of the DNA hybridized with RNA from larval nuclei. Competition experiments reveal that neurula nuclei contain copies of all the kinds of DNA-like RNA found in swimming larvae. Exhaustion experiments indicate that neurula nuclei contain a greater number of representatives of the class of D-RNA which is present in only a few copies relative to its homologous DNA sequences, as well as the D-RNA species which are present in numerous copies relative to their homologous DNA sequences, than do nuclei of later stages.
Published Version
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