Abstract
Objective: To evaluate the effect of intravitreal anti-vascular endothelial growth factor (anti-VEGF) injection on intraocular pressure (IOP) and ocular axial length (AL). Methods: A prospective series of consecutive patients undergoing injection of intravitreal bevacizumab or ranibizumab in our clinic was investigated. IOP was measured with Tono-Pen and ocular AL with ultrasound biometry before (IOP0, AL0) and about 1 min (IOP1, AL1) and 24 hours (IOP2, AL2) after intravitreal injection. Logistic regression analysis was used to investigate factors (lens status, presence of glaucoma and previous intravitreal injection) associated with increased IOP and AL. Results: We recruited 96 patients with a mean age of 66.7p12 years, 53 (55%) men and 43 (45%) women. One minute after the injection (IOP1), mean IOP increased from 15.2p3.5 mmHg (IOP0) to 22.2p8.6 mmHg (p
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