Analysis on clinical treatment of neovascular glaucoma with different intraocular pressure

Abstract

Objective To analyse the clinical efficacy of treatment of the neovascular glaucoma with different intraocular pressure. Methods A total of 111 eyes of 100 patients with neovascular glaucoma from September 2013 to December 2015 were enrolled .They according to the IOP before treatment were divided into four groups: Group A, 18-21 mmHg (1 mmHg=0.133 kPa) in 20 eyes of 19 cases; Group B, 22-30 mmHg in 30 eyes of 28 cases; Group C, 31-40 mmHg in 31 eyes of 28 cases; Group D, ≥41mmHg in 30 eyes of 25 cases .Group A and Group B received the panretinal photocoagulation, Group C received intravitreal ranibizumab injection firstly , then received the panretinal photocoagulation, Group D received intravitreal injection of ranibizumab firstly , then received the trabeculectomy combined with panretinal photocoagulation . At 1 week, 1 month and 3 months after treatment the intraocular pressure, corneal edema degree, iris neovascularization subsided and complications were observed. Results After treatment new vessels subsided in Group A was 17 eyes , Group B in 24 eyes, Group C in 26 eyes, and Group D in 22 eyes .In Group A, the difference in IOP between before and after treatment was not significant (P=0.342, 0.101, 0.591), the difference in IOP after treatment in other groups compared with before treatment was statistically significant (P=0.000). Conclusion Different treatments are used to treat patients with neovascular glaucoma with different intraocular pressure. Key words: Glaucoma, neovascular; Intraocular pressure; Ranibizumab; Trabeculectomy; Photocoagulation, panretinal