Abstract
Objective To evaluate the clinical efficacy of intravitreal Ranibizumab injection combined with Ex-Press implantation and panretinal photocoagulation for neovascular glaucoma. Methods The data of 39 eyes of 39 cases with neovascular glaucoma from Mar. 2015 to Jan. 2017 were collected and analyzed retrospectively. The patients had been randomly divided into two groups: the research group, 21 cases, were treated with Ranibizumab intravitreal injection combined with Ex-Press implantation ; the control group, 18 cases, were treated with Ranibizumab intravitreal injection combined with trabeculectomy and panretinal photocoagulation. The visual acuity, intraocular pressure, iris neovascular vessels, the operation successful rate and complications in both groups before and 1, 3, 6 months after surgery were observed and analyzed. Results The difference in BCVA before and 6 months after surgery were not statistically significant between two groups(P>0.05). The postoperative BCVA of two groups were improved, the difference was statistically significant between before and after surgery(χ2=11.183, 12.961, P=0.011, 0.005). The intraocular pressure after surgery were decreased in two groups, the difference was statistically significant between before and after surgery (P 0.05). The difference of operation successful rate were not statistically significant between two groups(χ2=0.550, P=0.458). The incidence of complications of group B was higer than that of group A, the difference was statistically significant between the two groups (χ2=4.353, P=0.037) . Conclusion Ex-Press implantation or trabeculectony combined with intravitreal ranibizumab injection and after surgery panretinal photocoagulation for NVG is safe and effective. The complications are less. Key words: Glaucoma, neovascular; Ex-Press implantation; Ranibizumab, intravitreal injection; photocoagulation, panretinal
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More From: Chinese Journal of Ocular Trauma and Occupational Eye Disease
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