Abstract

One of the most recent pharmacopoeial documents, the European Pharmacopoeia Supplement 9.4, inventories five new raw materials long known in Traditional Chinese Medicine (TCM). Part 1 and 2 present species providing new saponin raw materials: Bupleurum sp. and Platycodon grandiflorus. Part 3 describes Ligusticum chuanxiong which is a source of a new volatile oil-containing material. Part 4 is focused on Houttuynia cordata and Part 5 on Paeonia x suffruticosa (sources of a new flavonoid and terpenoid-phenolic raw material, respectively). Moreover, Supplement 9.4 describes two South American raw materials: guarana seed and mate leaf and an East Asian raw material – green tea leaf. Part 6 of the series of articles deals with botanical, ecological, chemical and pharmacological characterization of Paullinia cupana (guarana) which is a source of new alkaloid raw material – Guaranae semen. This material has long been known and used not only in South American countries but also in Europe as a psychostimulant due to a high content of caffeine. Currently, it advanced to be included in the list of pharmacopoeial raw materials in the European Union countries. The aim of the article is to provide the pharmaceutical and medical community with professional knowledge on Paullinia cupana, indispensable in contacts with patients.

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