Abstract

The specific characteristics of the pediatric population, the lack of evidence, as well as the small number of studies made treatment of septic shock in children one of the biggest challenges in intensive care units. The Surviving Sepsis Campaign issued in 2020 new guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. The first guide on this topic was published in 2004, and has been reviewed every four years since. Sepsis is a leading cause of healthcare utilization for children worldwide, and early recognition and appropriate management of children with sepsis and sepsis-associated organic dysfunction are crucial for the outcome. Although the new guidelines covered publications up to May 2017, this review also included some recently published studies. Following the innovations in this area, practical application and implementation of guidelines are important for the management of septic shock and sepsis-associated organ dysfunction in children.

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