Novel stereospecific dehydration of β-hydroxy-α-amino acids using Martin's sulfurane

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The stereospecific dehydration of threo- N-acyl-β-hydroxy-α-amino acid derivatives was performed using Martin's sulfurane to give ( Z)-α,β-dehydroamino acids, while erythro- N-acyl-β-hydroxy-α-amino acid amides were converted to 4,5- trans-oxazolines using analogous reaction conditions.