Abstract

In the May 2008 issue of Journal of Clinical Microbiology, Malhotra-Kumar et al. (2) provided an excellent minireview of current trends in rapid diagnostics for methicillin-resistant Staphylococcus aureus (MRSA) and glycopeptide-resistant enterococci. In this article, the authors describe a novel rapid culture-based assay, the 3M BacLite rapid MRSA test, which detects MRSA without the need for macroscopic growth of bacterial colonies, allowing the presence or absence of MRSA to be determined within 5 h. The article states the assay detects ciprofloxacin-resistant MRSA and comments that this may lead to the possibility of the assay not detecting community-acquired MRSA strains, as well as some hospital-acquired MRSA strains, that are sensitive to ciprofloxacin. The authors are correct in their statements but refer to an assay formulation that has not been available since February 2007, when ciprofloxacin was replaced by cefoxitin as a selective agent.

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